Meditrans Publication List

Journal Publications:

Banciu, M., Fens, M.H.A.M., Storm, G., Schiffelers, R.M. (2008). Antitumor activity and tumor localization of liposomal glucocorticoids in B16 melanoma-bearing mice. Journal of Controlled Release 127 (2), 131-136.

Banciu, M., Metselaar, J.M., Schiffelers, R.M. and Storm, G. (2008). Liposomal glucocorticoids as tumor-targeted anti-angiogenic nanomedicine in B16 melanoma-bearing mice. Journal of Steroid Biochemistry and Molecular Biology 111, 101-110.

Banciu, M., Metselaar, J.M., Schiffelers, R.M. and Storm, G. (2008). Antitumor activity of liposomal prednisolone phosphate depends on the presence of functional tumor-associated macrophages in tumor tissue. Neoplasia 10, 108-117.

Banciu, M., Schiffelers, R.M., Metselaar, J.M., and Storm, G. (2008). Utility of targeted glucocorticoids in cancer therapy. J Liposome Res 18, 47-57.

Banciu, M., Schiffelers, R.M. and Storm, G. (2008). Investigation into the role of tumor-associated macrophages in the antitumor activity of doxil. Pharmaceutical Research 25, 1948-1955.

Barge, A., Tei, L., Upadhyaya, D., Fedeli, F., Beltrami, L, Stefania, R., Aime, S. and Cravotto, G. (2008). Bifunctional ligands based on the DOTA-monoamide cage. Org. Biomol. Chem. 6, 1176-1184.

Boye Jensen, L., Morck Nielsen, H. and Foged, C. (2008). Dendritic Nanostructures as Carriers of Genetic Medicine. Lægemiddelforskning 2008, 13-15.

Cun, D., Boye Jensen, L., Mørck Nielsen, H., Moghimi, M., and Foged, C., (2008). Polymeric Nanocarriers for siRNA Delivery: Challenges and Future Prospects. Journal of Biomedical Nanotechnology, 4, 1–18.

Deckers, R., Rome, C. and Moonen, C.T. (2008). The role of ultrasound and magnetic resonance in local drug delivery. J Magn Reson Imaging 27, 400-409.

Delli Castelli, D., Gianolio, E., Geninatti Crich, S., Terreno, E. and Aime, S. (2008). Metal containing nanosized systems for MR-Molecular Imaging Applications. Coordination Chemistry Reviews, 252, 2424–2443.

Delli Castelli, D., Terreno, E., Carrera, C., Giovenzana, G., Mazzon, R., Rollet, S., Visigalli, M. and Aime, S. (2008). Lanthanide-Loaded Paramagnetic Liposomes as Switchable Magnetically Oriented Nanovesicles. Inorg. Chem., 47 (8), 2928–2930.

De Wolf, H.K., Johansson, N., Thong, A.T., Snel, C.J., Mastrobattista, E., Hennink, W.E. and Storm G. (2008). Plasmid CpG depletion improves degree and duration of tumor gene expression after intravenous administration of polyplexes. Pharmaceutical Research 25, 1654-1662.

De Wolf, H.K., Luten, J., Snel, C.J., Storm, G. and Hennink, W.E. (2008). Biodegradable, cationic methacrylamide-based polymers for gene delivery to ovarian cancer cells in mice. Molecular Pharmaceutics 5, 349-357.

Esposito, G., Geninatti Crich, S., and Aime, S. (2008). Efficient cellular labelling via CD44 receptors with cationic Liposomes functionalised with Hyaluronic Acid and loaded with contrast agents for MRI. Chemmedchem 3, 1858 – 1862.

Gianolio, E., Giovenzana, G.B, Ciampa, A., Lanzardo, S., Imperio, D., and Aime, S. (2008). A Novel Method of Cellular Labeling: Anchoring MR-Imaging Reporter Particles on the Outer Cell Surface. Chemmedchem 3, 60-62.

Hak, S., Sanders, H.M.H.F., Agrawal, P., Langereis, S., Gruell, H., Keizer, H.M., Arena, F., Terreno, E., Strijkers, G.J., and Nicolay, K. (2008). A high relaxivity Gd(III)DOTA-DSPE-based liposomal contrast agent for magnetic resonance imaging. Eur J Pharm Biopharm. Oct 10. [Epub ahead of print]

Koçer, A. (2007). A remote controlled valve in liposomes for triggered liposomal release. J Liposome Research 17 (3), 219 – 225.

Koçer, A., Walko, M., Feringa, B.L. (2007). Synthesis and utilization of reversible and irreversible light-activated nanovalves derived from the channel protein MscL. Nature Protocols 2 (6), 1426-1437.

Lammers, T., Hennink, W.E., and Storm, G. (2008). Tumour-targeted nanomedicines: Principles and practice. Brit J Cancer 99, 392-397.

Lammers, T., Subr, V., Peschke, P., Kuehnlein, R., Ulbrich, K., Hennink, W.E., Kiessling, F., Heilmann, M., Debus, J., Huber, P.E., and Storm, G. (2008). Image-guided and passively tumor-targeted polymeric nanomedicines for radiochemotherapy. Brit J Cancer 99, 900-910.

Langereis, S., Keupp, J., van Velthoven, J.L.J., de Roos, I.H.C., Burdinski, D., Pikkemaat, J.A., Grüll, H. (2009). A Temperature-Sensitive Liposomal 1H CEST and 19F Contrast Agent for MR Image-Guided Drug Delivery. J. Am. Chem. Soc. 131 (4), 1380–1381.

Lentacker, I., Wang, N., Vandenbroucke, R.E., De Smedt, S.C., Sanders, N.N. (2009). Ultrasound exposure of lipoplex coated microbubbles: intracellular rerouting can bypass their endolysosomal degradation. Molecular Pharmaceutics 6 (2), 457–467.

MacAleese, L., Stauber, J. and Heeren, R.M.A. (2009). Perspectives for imaging mass spectrometry in the proteomics landscape. Proteomics 9, 819-834.

Nolte-’t Hoen, E.N.M., Boot, E.P.J., Wagenaar-Hilbers, J.P.A., van Bilsen, J.H.M., Arkesteijn, G.J.A., Storm, G., Everse, L.A., van Eden, W. and Wauben, M.H.M. (2008). Identification and monitoring of effector and regulatory T cells during experimental arthritis based on differential expression of CD25 and CD134. Journal of Leukocyte Biology 83, 1-10.

Oliveira, S., Høgset. A., Storm, G. and Schiffelers, R.M. (2008). Delivery of siRNA to the Target Cell Cytoplasm: Photochemical Internalization Facilitates Endosomal Escape and Improves Silencing Efficiency, In Vitro and In Vivo. Current Pharmaceutical Design 14, 3686-3697.

Paasonen, L., Romberg, B., Storm, G., Yliperttula, M., Urtti, A. and Hennink W.E. (2007). Temperature-Sensitive Poly(N-(2-hydroxypropyl)methacrylamide mono/dilactate)-Coated Liposomes for Triggered Contents Release. Bioconjugate Chem., 18 (6), 2131–2136.

Pérez-Mayoral, E., Negri, V., Soler-Padrós, J., Cerdán, S. and Ballesteros, P. (2008). Chemistry of Paramagnetic and Diamagnetic Contrast Agents for Magnetic Resonance Imaging and Spectroscopy. pH Responsive Contrast Agents. European Journal of Radiology 67, 453 – 458.

Raemdonck, K., Demeester, J. and De Smedt, S.C. (2009). Advanced nanogel engineering for drug delivery. Soft Matter 5, 707–715.

Raemdonck, K., Vandenbroucke, R.E., Demeester, J., Sanders, N.N. and De Smedt, S.C. (2008). Maintaining the silence: reflections on long-term RNAi. Drug Discovery Today 13, 917-31.

Raemdonck, K., Van Thienen, T.G., Vandenbroucke, R.E., Sanders N.N., Demeester, J., and De Smedt, S.C. (2008). Dextran Microgels for Time-Controlled Delivery of siRNA. Advanced Functional Materials 18 (7), 993 – 1001.

Romberg, B., Flesch, F.M., Hennink, W.E. and Storm, G. (2008). Enzyme-induced shedding of a poly(amino acid)-coating triggers contents release from dioleoyl phosphatidylethanolamine liposomes. International Journal of Pharmaceutics 355, 108-113.

Romberg, B., Hennink, W.E. and Storm, G. (2008). Sheddable coatings for long-circulating nanoparticles. Pharmaceutical Research 25, 55-71.

Schiffelers, R.M., de Wolf, H.K., van Rooy, I., and Storm, G. (2007). Synthetic delivery systems for intravenous administration of nucleic acids. Nanomedicine 2, 169-181.

Schiffelers, R.M. and Storm, G. (2008) Liposomal nanomedicines as anticancer therapeutics: Beyond targeting tumor cells. International Journal of Pharmaceutics 364, 258-264.

Stancanello, J., Terreno, E., Delli Castelli, D., Cabella, C., Uggeri, F., and Aime, S. (2008). Development and validation of a smoothing-splines-based correction method for improving the analysis of CEST-MR images. Contr. Media Mol. Imaging 3, 136-149.

Stefania, R., Tei, L., Barge, A., Geninatti Crich, S., Szabo, I., Cabello, C., Cravotto, G., Aime, S. (2009). Tuning Glutamine Binding Modes in Gd-DOTA-Based Probes for an Improved MRI Visualization of Tumor Cells. Chemistry - A European Journal 15, 76-85.

Storm, G. (2007). EU Project MEDITRANS van start. Conceptuur 51; 20.

Talelli, M., Rijcken, C.J.F, Lammers, T., Seevinck, P.R., Storm, G., van Nostrum, C.F., Hennink, W.E. (2009). Superparamagnetic iron oxide nanoparticles encapsulated in biodegradable thermosensitive polymeric micelles: Towards a targeted nanomedicine suitable for image-guided drug delivery. Langmuir 25: 2060-2067.

Terreno, E., Barge, A., Beltrami, L., Cravotto, G., Delli Castelli, D., Fedeli, F., Jebasingh, B. and Aime, S. (2008). Highly shifted LIPOCEST agents based on the encapsulation of neutral polynuclear paramagnetic shift reagents. Chem. Commun. 600-602.

Terreno, E., Delli Castelli, D., Cabella, C., Dastru, W., Sanino, A., Stancanello, J., Tei, L., and Aime, S. (2008). Paramagnetic Liposomes as Innovative Contrast Agents for Magnetic Resonance (MR) Molecular Imaging Applications. Chem. Biodiv. 5, 1901-1912.

Terreno, E., Delli Castelli, D., Milone, L., Rollet, S., Stancello, J., Violante, E., and Aime, S. (2008). First ex-vivo MRI co-localisation of two LIPOCEST agents. Contrast Media and Molecular Imaging 3, 38-43.

Terreno, E., Sanino, A., Carrera, C., Delli Castelli, D., Giovenzana, G.B., Lombardi, A. Mazzon, R. Milone, L. Visigalli, M. and Aime, S. (2008). Determination of water permeability of paramagnetic liposomes of interest in MRI field. J Inorg Biochem. 102(5-6), 1112-1119.

Vandenbrouke, R.E., Lentacker, I., Demeester, J., De Smedt, S.C. and Sanders, N.N. (2008). Ultrasound assisted siRNA delivery using PEG-siPlex loaded microbubbles. Journal of controlled release 126, 265-273.

Van Thienen, T.G., Demeester, J. and De Smedt, S.C. (2008). Screening poly(ethyleneglycol) micro- and nanogels for drug delivery purposes. Int J Pharm. 351(1-2), 174-185.

Van Thienen, T. G., Raemdonck, K., Demeester, J., and De Smedt, S. C. (2007). Protein Release from Biodegradable Dextran Nanogels. Langmuir, 23 (19), 9794 -9801.

Van Tomme, S., Metselaar, J.M., Schiffelers, R.M. and Storm, G. (2008). Liposomal corticosteroids as targeted anti-inflammatory nanomedicine. Eur. Journal of Nanomedicine 1, 15-19.

Wentzel, B. (2006). Utrecht coordineert Europees Nanomedicines project. Conceptuur 47; 24.

Zeilmaker, R. (2006). Nanomedicijnen: Geleide projectielen voor het lichaam. Intermediair 20; 48-49.

Forthcoming Journal publications:

Buyens, K., Demeester, J., De Smedt, S.C. and Sanders, N.N. (2009). The HYDRA-protocol: a lab-scale method for encapsulation of siRNA in the core of PEGylated cationic liposomes. Langmuir Submitted

Buyens, K., Meyer, M., Wagner, E., Demeester, J., De Smedt, S.C. and Sanders, N.N. (2009). Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy. Angewandte Chemie In press

Cun, D., Foged, C., Yang, M., Frøkjær, S. and Nielsen, H.M. (2009): Preparation and Characterization of Biodegradable Poly (DL-lactide-co-glycolide) Nanoparticles as siRNA Carriers. Submitted to International Journal of Pharmaceutics

Foged, C., Vader, P., and Schiffelers, R. (2009). Lipid-based Formulations for Delivery of siRNA. In: Delivery Technologies for Biopharmaceuticals: Peptides, Proteins, Nucleic Acids and Vaccines, Joergensen, L. and Nielsen, H.M. (eds), Wiley, planned publication April 2009, In press

Heeren, R.M.A., Smith, D.F., Stauber, J., Kükrer-Kaletas, B. and MacAleese, L. (2008). Imaging mass spectrometry: Hype or Hope? Journal of the American Society for Mass Spectrometry In press.

Merkel, O.M., Beyerle, A., Librizzi, D., Pfestroff, A., Behr, T.M., Sproat, B., Barth, P.J. and Kissel, T. (2009). Non-viral siRNA delivery to the lung – investigation of PEG-PEI polyplexes and their in vivo performance. Molecular Pharmaceutics Submitted.

Merkel, O.M., Librizzi, D., Pfestroff, A., Schurrat, T., Buyens, K., De Smedt, S.C., Béhé, M. and Kissel, T. (2009). Influence of in vivo stability of various PEI/siRNA complexes on pharmacokinetics and biodistribution – A correlation study of fluorescence fluctuation spectroscopy and nuclear imaging data. Journal of Controlled Release Submitted

Merkel, O.M., Librizzi, D., Pfestroff, A., Schurrat, T., Buyens, K., Sanders, N.N., De Smedt, S.C., Béhé, M. and Kissel, T. (2009). Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-gpoly(ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging. Journal of Controlled Release Submitted.

Pacheco-Torres, J., López, P., Ballesteros, P. and Cerdán, S. (2009). Imaging the oxygen tension in tumors by magnetic resonance methods. In press

Raemdonck, K., Naeye, B., Buyens, K., Vandenbroucke, R.E., Hogset, A., Demeester, J., and De Smedt, S.C. (2009). Biodegradable Dextran Nanogels for RNAi: Focus on Endosomal Escape and Intracellular siRNA Delivery. Advanced Functional Materials In press.

Reul, R., Roesler, S., Benfer, M., Nguyen, J., Schmehl, T., Gessler, T., Weissmann, N., Seeger, W., Fink, L. and Kissel, T. (2009). Expression of functional folate receptors on the apical side of the mouse lung demonstrated using folate -PEG-rhodamine conjugates. In press

Righi, V., Roda, J.M., Paz, J., Mucci, A., Tugnoli, V., Barrios, L., Schenetti, L., Cerdán, S. and García-Martín, M.L. (2009). HR-MAS and genomic analysis of human tumor biopsies discriminates between high and low grade astrocytomas. NMR in Biomedicine In press

Rodrigues, T.B., López-Larrubia, P. and Cerdán, S. (2009). Redox Dependence and Compartmentation of (13C) Pyruvate in the brain of deuterated rats bearing implanted C6 gliomas. JNC In press

Stauber, J. and Heeren, R.M.A. (2009). Chapter II-4: Metal Enhanced, Matrix Enhanced SIMS, and MALDI. In: Surface Analysis and Techniques in Biology. In press.

Stauber, J., MacAleese, L., Franck, J., Snell, M., Claude, E., Kükrer-Kaletas, B., Wiel, I.M. van der, Wisztorski, M., Fournier, I. and Heeren, R.M.A. (2009). Protein Identification and imaging on FFPE and frozen tissues by MALDI-Ion mobility imaging Mass Spectrometry. Analytical Chemistry, Submitted.

Strijkers, G.J. and Nicolay, K. (2010). Relaxivity of Nanoparticles for Magnetic Resonance Imaging. In: Handbook of Nanophysics, 7 Volumes, 350 Chapters. Klaus D. Sattler, Editor. Taylor & Francis (CRC Press).

Tei, L., Mazooz, G., Barge, A., Shellef, Y., Ziv, K., Granot, D., Kalchenko, V., Dewhirst, M.W., Chaabane, L., Miragoli, L., Longo, D., Neeman, M. and Aime, S. (2009). Novel MRI and fluorescent probes responsive to the Factor XIII transglutaminase activity. In press

Van Thienen, T.G., Vercauteren, D., Van den Bossche, J., Thompson, D.H., Demeester, J. and De Smedt, S.C. (2009). Dextran nanogels with functional coatings: peg-lipid coated and ph sensitive lipid coated nanogels. International Journal of Pharmaceutics In press

Vercauteren, D., Vandenbroucke, R.E., Jones, A.T., Rejman, J., Demeester, J., De Smedt, S.C., Sanders, N.N. and Braeckmans, K. (2009). The use of inhibitors to study endocytic pathways of gene carriers: optimisation and pitfalls. Molecular Therapy In press

Conference publications:

Agrawal, P., Strijkers, G.J., van Lent, P., Blom, A., van den Berg, W., Crielaard, B., Lammers, T., Storm, G. and Nicolay, K. (2009). MRI to monitor Rheumatoid Arthritis disease progression and regression, following treatment with nanocarrier encapsulated drug. EuroNanoMedicine Abstract.

Agrawal, P., Strijkers, G.J., van Lent, P., Blom, A., van den Berg, W., Storm, G. and Nicolay, K. (2008). MRI to monitor disease progress in a mouse model of Rheumatoid Arthritis. ISMRM Benelux, 10 December 2008, Antwerp, Belgium.

Amann, A. and Gress, C. (2008). Development and pre-validation of an in-vitro method for the prediction of drug-drug interactions and intestinal absorptions as a tool for drug candidate selection. 10th Expert meeting on Blood Brain Barrier and Caco-2, Bad Herrenalb, Germany.

Boye Jensen, L. (2008). Polypropylene imine dendrimers as carriers of siRNA. 7th International Conference and Workshop on Biological Barriers and Nanomedicine – Advanced Drug Delivery and Predictive non vivo Testing Technologies.

Boye Jensen, L., Mørck Nielsen, H., Boas, U., Cun, D., Pittelkow, M., Christensen, J.B., Frøkjær, S. and Foged, C. (2008). Investigations of Poly(propyleneimine) Dendrimers as Carriers for siRNA Delivery. 7th International Conference and Workshop on Biological Barriers and Nanomedicine – Advanced Drug Delivery and Predictive non vivo Testing Technologies.

Boye Jensen, L., Mørck Nielsen, H., Boas, U., Cun, D., Pittelkow, M., Christensen, J.B., Frøkjær, S. and Foged, C. (2008). Investigations of Dendrimers as siRNA Delivery System. BIO-Dendrimer – 2008 Symposium on Biomedical Properties and Applications of Dendrimers, 3-5 July 2008, Lodz, Poland.

Buyens, K., Braeckmans, K., Demeester, J., De Smedt, S.C. and Sanders, N.N. (2009). ‘Single particle tracking’ for studying the aggregation of cationic liposomes in whole blood. EuroNanoMedicine Abstract.

Chaabane, L., Adage, T., Aime, S., Greco, B. and Zaratin, P. (2008). 'Differential degree of Blood Brain Barrier permeability during Experimental Autoimmune Encephalomyelitis measured by Gadolinium-enhancement MRI', poster presented at the World Congress on Treatment and Research in Multiple Sclerosis ACTRIMS-ECTRIMS-LACTRIMS (Montreal, Sept. 2008).

Collnot, E.-M., Bur, M., Leonard, F., Schmidt, C., Stallmach, A. and Lehr, C.-M. (2009). Nanoparticle in men against inflammatory bowel diseases – a promising approach for the therapy of diarrhoea. Clinam Meeting.

Collnot, E.-M., Leonard, F., Lehr, C.-M., (2009). The intestinal ‘enhanced permeability and retention effect’: a passive targeting principle for PLGA nanocarriers in the treatment of inflammatory bowel disease. Clinam Meeting.

Folz, J., Bur, M., Collnot, E., Crielaard, B.J., Lammers, T., Storm G. and Lehr C.-M. (2009). Reduced phagocytosis of pegylated nanosized liposomes by alveolar macrophages. EuroNanoMedicine Abstract.

Giraud, S. and Maskrot, H. (2008). Synthesis of iron containing nanopowders by the laser pyrolysis method for biomedical applications. (Abstract) Particles 2008, USA

Giraud, S. Maskrot, H. Bonville, P. and Boulanger L. (2008). Characterization of inorganic magnetic nanoparticles produced by the laser pyrolysis method. International Conference on Safe production and use of nanomaterials, Nanosafe 2008 November 3-7, 2008 – Grenoble, France.

Gress, C. and Amann, A. (2008). Effects of different parameters in Caco-2 bi-directional permeability studies. 10th Expert meeting on Blood Brain Barrier and Caco-2, Bad Herrenalb, Germany.

Hak, S., Sanders, E., Agrawal, P., Langereis, S., Gruell, H., Keizer, H., Arena, F., Terreno, E., Strijkers, G.J. and Nicolay, K. (2008). A High Relaxivity Gd(III)DOTA-DSPE-Based Liposomal Contrast Agent for Target-Specific MRI. Abstract for 2008 World Molecular Imaging Congress, Sept. 10–13, Nice, France.

Jensen, L.B., Mortensen, K., Jensen, D.K., Nielsen, H.M. and Foged, C. (2009). Characterization of siRNA-Dendrimer complexes by SAXS analysis. Poster presentation at 36th Annual Meeting & Exposition of the Controlled Release Society, July 18-22, Copenhagen, Denmark.

Keupp, J., Langereis S., de Roos, I., Burdinski, D., Pikkemaat, J. and Gruell, H. (2009). 1H-CEST and 19F MRI of temperature-responsive liposomal contrast agents for image guided drug delivery. ISMRM Conference, Hawaii, 18-24 April 2009.

Lammers, T., Subr, V., Ulbrich, K., Peschke, P., Kiessling, F., Huber, P.E., Hennink, W.E., and Storm, G. (2008). Carrier-based radiochemotherapy. CRS Abstract.

Lentacker, I., De Smedt, S.C. and Sanders N. (2009). Lipoplex loaded microbubbles for ultrasound triggered gene delivery. EuroNanoMedicine Abstract.

Leonard, F., Collnot, E.-M., Lehr, C.-M. (2008). Development of a novel 3D inflamed intestinal mucosa model: Initiation of inflammation in Caco-2 cells. 7th International Conference and Workshop on Biological Barriers and Nanomedicine – Advanced Drug Delivery and Predictive non vivo Testing Technologies.

Leonard, F., Collnot, E.-M., Lehr, C.-M. (2008). Development of a novel Caco-2 based 3D model of the inflamed intestinal mucosa: Initiation of inflammation. CRS Abstract.

Leonard, F., Collnot, E.-M., Lehr, C.-M. (2009). The intestinal ‘enhanced permeability and retention effect’: passive targeting of PLGA nanocarriers in the treatment of Crohn’s disease. EuroNanoMedicine Abstract.

Leonard, F., Collnot, E.-M., Lehr, C.-M. (2009). Development of a 3D in vitro model of the inflamed colonic mucosa. Congress on Alternatives & Animal Use in the Life Sciences Abstract. Rome.

MacAleese, L., Stauber, J. and Heeren, R.M.A. (2008). Imaging MS/MS: challenges for on-tissue protein identification. HUPO 7th Annual World Congress, Amsterdam (NL) 16-20.08.08.

Merkel, O.M., Beyerle, A., Librizzi, D. and Kissel, T. (2009). Imaging-guided Gene & Cell based Therapies Nuclear Imaging of Intratracheal siRNA Delivery with PEG-PEI Copolymers. 4th European Molecular Imaging Meeting - Barcelona 27-30 May 2009.

Naeye B., Raemdonck K., Demeester, J., De Smedt S.C. (2008). Pegylation of biodegradable dextran nanogels for controlled siRNA release. ESF-UB conference: Nanomedicine 2008, Sant Feliu de Guixols, Spain.

Naeye B., Raemdonck K., and De Smedt S.C. (2009). Optimization of biodegrabable dextran nanogels for controlled siRNA delivery. EuroNanoMedicine Abstract.

Raemdonck, K., Demeester, J., De Smedt, S.C. (2008). Intracellular time-controlled delivery of siRNA from cationic nanogel depots. 11th annual Meeting of the American Society of Gene Therapy (ASGT), May 28-June 1, Boston, Massachusetts, USA

Raemdonck, K., Demeester, J., De Smedt, S.C. (2008). Cytosolic nanogel depots for time-controlled siRNA delivery. 2nd International Symposium on Cellular Delivery of Therapeutic Macromolecules Cardiff University, June 22nd – June 25th

Raemdonck, K., Demeester, J., De Smedt, S.C. (2008). Cytosolic nanogel depots for time-controlled siRNA delivery. September 16th – September 18th, Stockholm international fairs and congress center, Stockholm, Sweden.

Raemdonck, K., Demeester, J., De Smedt, S.C. (2008). Cytosolic nanogel depots for time-controlled siRNA delivery. Right Symposium “RNA interference technology as Human Therapeutic Tool”, 3-5 November, The International Auditorium, Brussels

Raemdonck, K., Naeye B., Demeester, J., De Smedt, S.C. (2009). Evaluation of a dextran nanogel concept for intracellular siRNA delivery. EuroNanoMedicine Abstract.

Ratzinger, G., Agrawal, P., Wirth, M., Körner, W., Nicolay, K. and Gabor, F. (2009). Gadolinium-labeled PLGA Nanoparticles for Magnetic Resonance Imaging. Presented at the 21st Scientific Congress of the Austrian Pharmaceutical Society April 16th to April 18th 2009, Vienna, Austria.

Schiffelers, R., Oliveira, S., Woodle, M., Hogset, A. and Storm, G. (2008). TARGETED NANOMEDICINES DELIVERING siRNA. Potentiation of Silencing Activity by Photochemical Internalization. CRS Abstract.

Stauber, J., Klerk, L., van Bochove, G.S., Nicolay, K. and Heeren, R.M.A. (2008). A Combined Imaging Mass spectrometry and MRI study of nanoparticle based drug delivery systems. HUPO 7th Annual World Congress, Amsterdam (NL) 16-20.08.08.

Stauber, J., Kükrer-Kaletas, B., van der Wiel, I.M., Heeren, R.M.A., Snel, M.F. and Claude, E. (2008). Ion mobility Imaging Mass Spectrometry: A New Tool for In situ Identification. 56th ASMS Conference on Mass Spectrometry and Applied Topics, Dencer, CO (USA). 1-5.06.08.

Stauber J., MacAleese L., Franck J., Snel M., Claude E., Kükrer Kaletas B., Wiel I. M. van der, Wisztorski M., Fournier I. and Heeren, R.M.A. (2008). Targeted Ion Mobility Imaging Mass Spectrometry: A new tool for In situ identification. HUPO 7th Annual World Congress, Amsterdam (NL) 16-20.08.08.

UNITO (2007). Inclusion and Aggregation Properties of an Anionic Porphyrin with Ionic and Non-Ionic Cyclodextrin Vesicles for Diagnostic Applications. 19-22 September 2007 – Poster presented at the 8th National Congress on Supramolecular Chemistry held in Trieste (Italy).

Theses:

S.S. Oliveira. Utrecht 08-12-08. Title: Epidermal growth factor receptor: Target for delivery and silencing. Promotor: Prof. Dr. G. Storm. Copromotor, Dr. R.M. Schiffelers.

An Integrated Project funded by the European Commission under the "nanotechnologies and nano-sciences, knowledge-based multifunctional materials and new production processes and devices" (NMP) thematic priority of the Sixth Framework Programme. Contract Number: NMP4-CT-2006-026668